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Title: Atherosclerotic plaque formation in the coronary arteries
Authors: Saveljic I.
Nikolic, Dalibor
Milosevic Z.
Filipovic, Nenad
Journal: IFMBE Proceedings
Issue Date: 1-Jan-2020
Abstract: © Springer Nature Switzerland AG 2020. Atherosclerosis is a disease of arterial blood vessels characterized by the accumulation of lipids in the arterial wall, starting with endothelial dysfunction, which favors lipid and cell elements crossing inside blood vessel wall. In this study, using DICOM images, a numerical model of atherosclerosis progression was developed. Fluid domain (blood) was modeled using Navier-Stokes equations in conjunction with continuity equation, while the solid domain (arterial wall) was modeled using Darcy’s law. For the purpose of modeling lowdensity lipoprotein (LDL) and oxygen transport, convection-diffusion equations were used. Kedem-Katchalsky equations were used for coupling fluid and solid dynamics. Determination of plaque location and plaque volume with computer simulation for a specific patient shows a potential benefit for prediction of disease progression. The results for plaque concentration for the right and left coronary arteries are presented.
Type: Conference Paper
DOI: 10.1007/978-3-030-17971-7_48
ISSN: 16800737
SCOPUS: 85066019727
Appears in Collections:Faculty of Engineering, Kragujevac
Institute for Information Technologies, Kragujevac
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