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Title: Computational modeling of plaque progression in coronary arteries
Authors: Radović M.
Isailovic, Velibor
Saveljic I.
Milosevic Z.
Nikolic, Dalibor
Exarchos T.
Fotiadis D.
Parodi O.
Filipovic, Nenad
Journal: 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015
Issue Date: 28-Dec-2015
Abstract: © 2015 IEEE. Atherosclerosis is a medical condition becoming the number one cause of death worldwide. For this reason, any developement that may help physicians in early diagnostic and selection of the most appropriate treatment strategy is of great importance. In this paper we describe three-dimensional computer model of plaque formation and development for human coronary artery. In order to validate proposed model we used ten specific patients from CT study belonging to one of the following groups: (1) de-novo group - patients with new formed plaques, (2) old-lesions group - patients with plaques with progression and (3) control group - patients with plaques without progression. Plaque volume progression is fitted by using two time points for baseline and follow up. Results obtained within this study indicate high potential of this model to be used in clinical practice, thus assisting physicians by providing them valuable information about future disease progression.
Type: Conference Paper
DOI: 10.1109/BIBE.2015.7367648
SCOPUS: 84962861095
Appears in Collections:Faculty of Engineering, Kragujevac
Institute for Information Technologies, Kragujevac
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