Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/14503
Title: IN VIVO PROTEKTIVNI EFEKAT EKSTRAKATA BILJKE Lysimachia vulgaris NA DNK OŠTEĆENJA INDUKOVANA ETIL METANSULFONATOM 2022ЗБОРНИК БИОДИВЕРЗИТЕТ
Authors: Matić, Sanja
Sreckovic, Nikola
Katanić Stanković, Jelena S.
Mihailovic, Vladimir
Journal: Zbornik radova / XXVII savetovanje o biotehnologiji sa međunarodnim učešćem
Issue Date: Mar-2022
Abstract: The in vivo genotoxic activity of the aerial part and root methanol extracts of Lysimachia vulgaris L. and ability to protect DNA from ethyl methanesulfonate- induced DNA damage was studied using comet assays in Drosophila melanogaster. Results revealed no significant differences in mean genetic damage index between exposure groups (20, 40, 80 mg mL-1 of Drosophila food) and negative control, indicating a non-genotoxic effect. Combined treatment of extracts and ethyl methanesulfonate showed a significant reduction in DNA damage with a percentage of reduction above 80. These findings suggest that the methanolic extract of L. vulgaris could be used as a natural agent in the prevention of diseases associated with DNA damage.
URI: https://scidar.kg.ac.rs/handle/123456789/14503
Type: conference paper
DOI: 10.46793/SBT27.523M
Appears in Collections:Institute for Information Technologies, Kragujevac

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