Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/19279
Title: New dinuclear Au(III) complex: Synthesis, characterization and study of the interections with DNA
Authors: Radisavljević, Snežana
Jovanovic P.
Kesić, Ana
Petrović, Biljana
Issue Date: 2022
Abstract: Considering that gold(III) complexes are isostructural and isoelectronic with platinum(II) complexes, the synthesis, characterization and study of their biological activity were very common in the last few years. We have synthesized new dinuclear gold(III) complex with 1.5-naphtiridine as bridging ligand. The structure of this complex was confirmed by different analytical methods (IR, UV-Vis,1H NMR, mass analysis, conductometry). The study of the interactions between complex and DNA was performed by UV-Vis spectrofotometry, fluorescence spectroscopy and viscosity measurement. Based on the results of UV-Vis spectrofotometry can be concluded that complex binds to DNA. According to the results obtained by fluorescence spectroscopy and by viscosity measurement, the covalent binding mode between complex and DNA was confirmed.
URI: https://scidar.kg.ac.rs/handle/123456789/19279
Type: conferenceObject
Appears in Collections:Institute for Information Technologies, Kragujevac

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