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Title: In vitro cytotoxic activity of origanum vulgare L. On HCT-116 and MDA-MB-231 cell lines
Authors: Grbović, Filip
Stankovíc M.
Ćurčić Milutinović, Milena
Đorđević, Nevena
Šeklić, Dragana
Topuzovic, Marina
Marković, Snežana
Journal: Plants
Issue Date: 1-Sep-2013
Abstract: © 2013 by the authors; licensee MDPI, Basel, Switzerland. In the present investigation, we examined the cytotoxic effect of methanolic extract from Origanum vulgare on HCT-116 and MDA-MB-231 cell line in vitro. In order to determine the cytotoxic effects we used an MTT viability assay. The results showed that cell growth is significantly lower in extract treated cells compared to untreated control. The effect of inhibition of cell growth was higher in the treatment of HCT-116 cell line than in MDA-MB-231. Based on the results it is determined that O. vulgare is a significant source of biologically active substances that have cytotoxic and antiproliferative activity in vitro.
Type: Article
DOI: 10.3390/plants2030371
SCOPUS: 84938588584
Appears in Collections:Faculty of Science, Kragujevac
Institute for Information Technologies, Kragujevac
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